Any suggestions for relieving anxiety in dogs?

Trying calmicalm but it is not working. Four year old Beagle that whines and crys when left alone for even a minute. About to pull my hair out. Please help.

Trying a desensitization program, coupled with the medication and perhaps DAP room diffuser and spray on bedding, a bandana, etc. may be more effective than just the medication alone. This is usually accomplished most successfully with the help of a professional animal behaviorist. I have included links though to help get you started. Doggy day care once or twice a week also seems to help (or finding someone you can leave the dog with a few times a week) while you work on the desensitization. Busy toys also seem to help some dogs if they are not so upset that they aren’t interested in treats. Good luck.

Dog Owner Basics : How to Deal With Separation Anxiety in Dogs