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Nervous System

20 June 2010 No Comment

Nervous System
How do chemotherapy drugs affect the nervous system?

Hi I need to know how chemotherapy drugs affect the nervous system. And the side affects caused by them on the nervous system.

Chemotherapy adversely affects cognitive function both acutely and chronically, but little is known about the underlying mechanisms. A new study shows that short-term chemotherapy causes not only acute injury to progenitor cells, but also delayed damage to myelin.

Some chemotherapy drugs can cause direct or indirect changes in the central nervous system (brain and spinal cord), the cranial nerves, or peripheral nerves. The cranial nerves are connected directly to the brain and are important for movement and touch sensation (feeling) of the head, face, and neck. Cranial nerves are also important for vision, hearing, taste, and smell. Peripheral nerves lead to and from the rest of the body and are important in movement, touch sensation, and regulating activities of some internal organs.

A few chemotherapy drugs, for example cisplatin or vincristine, can permanently damage parts of the nervous system. Although it is not yet proven, these drugs may interfere with the nerves that control erection.-


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